A lesion-selective albumin-CTLA4Ig as a safe and effective treatment for collagen-induced arthritis

BACKGROUND: CTLA4Ig is a dimeric fusion protein of the extracellular domain of cytotoxic T-lymphocyte protein 4 (CTLA4) and an Fc (Ig) fragment of human IgG(1) that is approved for treating rheumatoid arthritis. However, CTLA4Ig may induce adverse effects. Developing a lesion-selective variant of CT...

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Detalles Bibliográficos
Autores principales: Jiang, Fu-Yao, Zhang, Yan-Zhu, Tai, Yuan-Hong, Chou, Chien-Yu, Hsieh, Yu-Ching, Chang, Ya-Chi, Huang, Hsiao-Chen, Li, Zhi-Qin, Hsieh, Yuan-Chin, Chen, I-Ju, Huang, Bo-Cheng, Su, Yu-Cheng, Lin, Wen-Wei, Lin, Hsin-Chieh, Chao, Jui-I, Yuan, Shyng-Shiou F., Wang, Yun-Ming, Cheng, Tian-Lu, Tzou, Shey-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933273/
https://www.ncbi.nlm.nih.gov/pubmed/36797799
http://dx.doi.org/10.1186/s41232-023-00264-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933273/
https://www.ncbi.nlm.nih.gov/pubmed/36797799
http://dx.doi.org/10.1186/s41232-023-00264-8

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