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Early activation of Toll-like receptor-3 reduces the pathological progression of Alzheimer’s disease in APP/PS1 mouse

BACKGROUND: Toll-like receptor 3 (TLR3) plays an important role in the immune/inflammatory response in the nervous system and is a main pathological feature of Alzheimer’s disease (AD). This study investigates the role of early activation of TLR3 in the pathophysiological process of AD. METHODS: In...

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Detalles Bibliográficos
Autores principales: Wang, Shang, Zhu, Taiyang, Ni, Wanyan, Zhou, Chao, Zhou, Hui, Lin, Li, Hu, Yuting, Sun, Xiaoyu, Han, Jingjing, Zhou, Yan, Jin, Guoliang, Zu, Jie, Shi, Hongjuan, Yang, Xingxing, Zhang, Zuohui, Hua, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933297/
https://www.ncbi.nlm.nih.gov/pubmed/36797783
http://dx.doi.org/10.1186/s13195-023-01186-w