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Novel Thiopyrano[2,3-d]thiazole-pyrazole Hybrids as Potential Nonsulfonamide Human Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, and Biochemical Studies

[Image: see text] In recent years, molecular hybridization strategies have developed into a potent strategy for drug discovery. A series of novel thiopyrano[2,3-d]thiazoles linked to the pyrazole moiety was designed and developed as anticancer agents by a molecular hybridization. Target compounds we...

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Detalles Bibliográficos
Autores principales: Metwally, Nadia Hanafy, El-Desoky, Ebrahim Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933482/
https://www.ncbi.nlm.nih.gov/pubmed/36816682
http://dx.doi.org/10.1021/acsomega.2c06954