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Interleukin 27 is a novel cytokine with anti-inflammatory effects against spondyloarthritis through the suppression of Th17 responses

INTRODUCTION: Spondylarthritis (SpA) development in HLA-B27/human β2-microglobulin transgenic rat (B27-rat) is correlated with altered conventional dendritic cell (cDC) function that promotes an inflammatory pattern of CD4+T cells, including a biased expansion of pro-inflammatory Th(17) population a...

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Detalles Bibliográficos
Autores principales: Jouhault, Quentin, Cherqaoui, Bilade, Jobart-Malfait, Aude, Glatigny, Simon, Lauraine, Marc, Hulot, Audrey, Morelle, Guillaume, Hagege, Benjamin, Ermoza, Kétia, El Marjou, Ahmed, Izac, Brigitte, Saintpierre, Benjamin, Letourneur, Franck, Rémy, Séverine, Anegon, Ignacio, Boissier, Marie-Christophe, Chiocchia, Gilles, Breban, Maxime, Araujo, Luiza M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933703/
https://www.ncbi.nlm.nih.gov/pubmed/36818477
http://dx.doi.org/10.3389/fimmu.2022.1072420