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Circulating microRNAs as promising testicular translatable safety biomarkers: current state and future perspectives

Drug-induced testicular injury (DITI) is one of the often-observed and challenging safety issues seen during drug development. Semen analysis and circulating hormones currently utilized have significant gaps in their ability to detect testicular damage accurately. In addition, no biomarkers enable a...

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Detalles Bibliográficos
Autores principales: Zhang, Jiangwei, Campion, Sarah, Catlin, Natasha, Reagan, William J., Palyada, Kiran, Ramaiah, Shashi K., Ramanathan, Ragu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933818/
https://www.ncbi.nlm.nih.gov/pubmed/36795116
http://dx.doi.org/10.1007/s00204-023-03460-0