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Engineering cytokine therapeutics

Cytokines have pivotal roles in immunity, making them attractive as therapeutics for a variety of immune-related disorders. However, the widespread clinical use of cytokines has been limited by their short blood half-lives and severe side effects caused by low specificity and unfavourable biodistrib...

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Detalles Bibliográficos
Autores principales: Deckers, Jeroen, Anbergen, Tom, Hokke, Ayla M., de Dreu, Anne, Schrijver, David P., de Bruin, Koen, Toner, Yohana C., Beldman, Thijs J., Spangler, Jamie B., de Greef, Tom F. A., Grisoni, Francesca, van der Meel, Roy, Joosten, Leo A. B., Merkx, Maarten, Netea, Mihai G., Mulder, Willem J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933837/
https://www.ncbi.nlm.nih.gov/pubmed/37064653
http://dx.doi.org/10.1038/s44222-023-00030-y