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Engineering cytokine therapeutics
Cytokines have pivotal roles in immunity, making them attractive as therapeutics for a variety of immune-related disorders. However, the widespread clinical use of cytokines has been limited by their short blood half-lives and severe side effects caused by low specificity and unfavourable biodistrib...
Autores principales: | Deckers, Jeroen, Anbergen, Tom, Hokke, Ayla M., de Dreu, Anne, Schrijver, David P., de Bruin, Koen, Toner, Yohana C., Beldman, Thijs J., Spangler, Jamie B., de Greef, Tom F. A., Grisoni, Francesca, van der Meel, Roy, Joosten, Leo A. B., Merkx, Maarten, Netea, Mihai G., Mulder, Willem J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933837/ https://www.ncbi.nlm.nih.gov/pubmed/37064653 http://dx.doi.org/10.1038/s44222-023-00030-y |
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