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NIAPU: network-informed adaptive positive-unlabeled learning for disease gene identification

MOTIVATION: Gene–disease associations are fundamental for understanding disease etiology and developing effective interventions and treatments. Identifying genes not yet associated with a disease due to a lack of studies is a challenging task in which prioritization based on prior knowledge is an im...

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Detalles Bibliográficos
Autores principales: Stolfi, Paola, Mastropietro, Andrea, Pasculli, Giuseppe, Tieri, Paolo, Vergni, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933847/
https://www.ncbi.nlm.nih.gov/pubmed/36727493
http://dx.doi.org/10.1093/bioinformatics/btac848