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Cox regression using a calendar time scale was unbiased in simulations of COVID-19 vaccine effectiveness & safety

BACKGROUND: Observational studies on corona virus disease 2019 (COVID-19) vaccines compare event rates in vaccinated and unvaccinated person time using Poisson or Cox regression. In Cox regression, the chosen time scale needs to account for the time-varying incidence of severe acute respiratory synd...

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Detalles Bibliográficos
Autores principales: Lund, Lars Christian, Støvring, Henrik, Pottegård, Anton, Andersen, Morten, Hallas, Jesper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933854/
https://www.ncbi.nlm.nih.gov/pubmed/36806733
http://dx.doi.org/10.1016/j.jclinepi.2023.02.012