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Intralymphatic glutamic acid decarboxylase administration in type 1 diabetes patients induced a distinctive early immune response in patients with DR3DQ2 haplotype

GAD-alum given into lymph nodes to Type 1 diabetes (T1D) patients participating in a multicenter, randomized, placebo-controlled double-blind study seemed to have a positive effect for patients with DR3DQ2 haplotype, who showed better preservation of C-peptide than the placebo group. Here we compare...

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Detalles Bibliográficos
Autores principales: Puente-Marin, Sara, Dietrich, Fabrícia, Achenbach, Peter, Barcenilla, Hugo, Ludvigsson, Johnny, Casas, Rosaura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933867/
https://www.ncbi.nlm.nih.gov/pubmed/36817467
http://dx.doi.org/10.3389/fimmu.2023.1112570