Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging

Protein quality control is important for healthy aging and is dysregulated in age-related diseases. The autophagy-lysosome and ubiquitin-proteasome are key for proteostasis, but it remains largely unknown whether other proteolytic systems also contribute to maintain proteostasis during aging. Here,...

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Detalles Bibliográficos
Autores principales: Jiao, Jianqin, Curley, Michelle, Graca, Flavia A., Robles-Murguia, Maricela, Shirinifard, Abbas, Finkelstein, David, Xu, Beisi, Fan, Yiping, Demontis, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933915/
https://www.ncbi.nlm.nih.gov/pubmed/36640359
http://dx.doi.org/10.1016/j.celrep.2022.111970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933915/
https://www.ncbi.nlm.nih.gov/pubmed/36640359
http://dx.doi.org/10.1016/j.celrep.2022.111970

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