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Modulation of protease expression by the transcription factor Ptx1/PITX regulates protein quality control during aging
Protein quality control is important for healthy aging and is dysregulated in age-related diseases. The autophagy-lysosome and ubiquitin-proteasome are key for proteostasis, but it remains largely unknown whether other proteolytic systems also contribute to maintain proteostasis during aging. Here,...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933915/ https://www.ncbi.nlm.nih.gov/pubmed/36640359 http://dx.doi.org/10.1016/j.celrep.2022.111970 |