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Early Treatment with Pegylated Interferon Lambda for Covid-19

BACKGROUND: The efficacy of a single dose of pegylated interferon lambda in preventing clinical events among outpatients with acute symptomatic coronavirus disease 2019 (Covid-19) is unclear. METHODS: We conducted a randomized, controlled, adaptive platform trial involving predominantly vaccinated a...

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Detalles Bibliográficos
Autores principales: Reis, Gilmar, Moreira Silva, Eduardo A.S., Medeiros Silva, Daniela C., Thabane, Lehana, Campos, Vitoria H.S., Ferreira, Thiago S., Santos, Castilho V.Q., Nogueira, Ana M.R., Almeida, Ana P.F.G., Savassi, Leonardo C.M., Figueiredo-Neto, Adhemar D., Dias, Ana C.F., Freire Júnior, Adelino M., Bitarães, Carina, Milagres, Aline C., Callegari, Eduardo D., Simplicio, Maria I.C., Ribeiro, Luciene B., Oliveira, Rosemary, Harari, Ofir, Wilson, Lindsay A., Forrest, Jamie I., Ruton, Hinda, Sprague, Sheila, McKay, Paula, Guo, Christina M., Limbrick-Oldfield, Eve H., Kanters, Steve, Guyatt, Gordon H., Rayner, Craig R., Kandel, Christopher, Biondi, Mia J., Kozak, Robert, Hansen, Bettina, Zahoor, M. Atif, Arora, Paul, Hislop, Colin, Choong, Ingrid, Feld, Jordan J., Mills, Edward J., Glenn, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9933926/
https://www.ncbi.nlm.nih.gov/pubmed/36780676
http://dx.doi.org/10.1056/NEJMoa2209760