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Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models

There is an urgent need to develop novel drugs to reduce the mortality from severe infectious diseases with the emergence of new pathogens, including Coronavirus disease 2019 (COVID-19). Although current drugs effectively suppress the proliferation of pathogens, immune cell activation, and inflammat...

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Detalles Bibliográficos
Autores principales: Morita, Maaya, Yoneda, Aki, Tokunoh, Nagisa, Masaki, Tatsumi, Shirakura, Keisuke, Kinoshita, Mayumi, Hashimoto, Rina, Shigesada, Naoya, Takahashi, Junya, Tachibana, Masashi, Tanaka, Shota, Obana, Masanori, Hino, Nobumasa, Ikawa, Masahito, Tsujikawa, Kazutake, Ono, Chikako, Matsuura, Yoshiharu, Kidoya, Hiroyasu, Takakura, Nobuyuki, Kubota, Yoshiaki, Doi, Takefumi, Takayama, Kazuo, Yoshioka, Yasuo, Fujio, Yasushi, Okada, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934020/
https://www.ncbi.nlm.nih.gov/pubmed/36634143
http://dx.doi.org/10.1073/pnas.2213317120