Cargando…
Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models
There is an urgent need to develop novel drugs to reduce the mortality from severe infectious diseases with the emergence of new pathogens, including Coronavirus disease 2019 (COVID-19). Although current drugs effectively suppress the proliferation of pathogens, immune cell activation, and inflammat...
Autores principales: | Morita, Maaya, Yoneda, Aki, Tokunoh, Nagisa, Masaki, Tatsumi, Shirakura, Keisuke, Kinoshita, Mayumi, Hashimoto, Rina, Shigesada, Naoya, Takahashi, Junya, Tachibana, Masashi, Tanaka, Shota, Obana, Masanori, Hino, Nobumasa, Ikawa, Masahito, Tsujikawa, Kazutake, Ono, Chikako, Matsuura, Yoshiharu, Kidoya, Hiroyasu, Takakura, Nobuyuki, Kubota, Yoshiaki, Doi, Takefumi, Takayama, Kazuo, Yoshioka, Yasuo, Fujio, Yasushi, Okada, Yoshiaki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934020/ https://www.ncbi.nlm.nih.gov/pubmed/36634143 http://dx.doi.org/10.1073/pnas.2213317120 |
Ejemplares similares
-
SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression
por: Hashimoto, Rina, et al.
Publicado: (2022) -
ETV2-TET1/TET2 Complexes Induce Endothelial Cell-Specific Robo4 Expression via Promoter Demethylation
por: Tanaka, Toru, et al.
Publicado: (2018) -
Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization
por: Hu, Liuying, et al.
Publicado: (2021) -
A nasal vaccine with inactivated whole-virion elicits protective mucosal immunity against SARS-CoV-2 in mice
por: Tokunoh, Nagisa, et al.
Publicado: (2023) -
Apelin as a marker for monitoring the tumor vessel normalization window during antiangiogenic therapy
por: Zhang, Li, et al.
Publicado: (2015)