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Neuronal membrane proteasomes regulate neuronal circuit activity in vivo and are required for learning-induced behavioral plasticity

Protein degradation is critical for brain function through processes that remain incompletely understood. Here, we investigated the in vivo function of the 20S neuronal membrane proteasome (NMP) in the brain of Xenopus laevis tadpoles. With biochemistry, immunohistochemistry, and electron microscopy...

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Detalles Bibliográficos
Autores principales: He, Hai-yan, Ahsan, Arifa, Bera, Reshmi, McLain, Natalie, Faulkner, Regina, Ramachandran, Kapil V., Margolis, Seth S., Cline, Hollis T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934054/
https://www.ncbi.nlm.nih.gov/pubmed/36630455
http://dx.doi.org/10.1073/pnas.2216537120