Cargando…
Neuronal membrane proteasomes regulate neuronal circuit activity in vivo and are required for learning-induced behavioral plasticity
Protein degradation is critical for brain function through processes that remain incompletely understood. Here, we investigated the in vivo function of the 20S neuronal membrane proteasome (NMP) in the brain of Xenopus laevis tadpoles. With biochemistry, immunohistochemistry, and electron microscopy...
Autores principales: | He, Hai-yan, Ahsan, Arifa, Bera, Reshmi, McLain, Natalie, Faulkner, Regina, Ramachandran, Kapil V., Margolis, Seth S., Cline, Hollis T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934054/ https://www.ncbi.nlm.nih.gov/pubmed/36630455 http://dx.doi.org/10.1073/pnas.2216537120 |
Ejemplares similares
-
A mammalian nervous system-specific plasma membrane proteasome complex that modulates neuronal function
por: Ramachandran, Kapil V., et al.
Publicado: (2017) -
Photoactivatable Dopamine and Sulpiride to Explore
the Function of Dopaminergic Neurons and Circuits
por: Asad, Naeem, et al.
Publicado: (2020) -
Notch Is Required in Adult Drosophila Sensory Neurons for Morphological and Functional Plasticity of the Olfactory Circuit
por: Kidd, Simon, et al.
Publicado: (2015) -
Role of the visual experience-dependent nascent proteome in neuronal plasticity
por: Liu, Han-Hsuan, et al.
Publicado: (2018) -
Requirement of dendritic Akt degradation by the ubiquitin–proteasome system for neuronal polarity
por: Yan, Dong, et al.
Publicado: (2006)