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Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane

The urokinase-type plasminogen activator (uPA) system consists of the proteinase uPA, its receptor (PLAUR/uPAR). Under physiological conditions, uPA and PLAUR are predominantly expressed by blood cells, including neutrophils, monocytes, and macrophages, and play important roles in cell activation, a...

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Detalles Bibliográficos
Autores principales: Pang, Hailin, Ouyang, Jiayue, Yang, Zengwen, Shang, Hong, Liang, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934069/
https://www.ncbi.nlm.nih.gov/pubmed/36638209
http://dx.doi.org/10.1073/pnas.2212991120