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ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes

Monocytes play a key role in innate immunity by eliminating pathogens, releasing high levels of cytokines, and differentiating into several cell types, including macrophages and dendritic cells. Similar to other phagocytes, monocytes produce superoxide anions through the NADPH oxidase complex, which...

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Detalles Bibliográficos
Autores principales: Tlili, Asma, Pintard, Coralie, Hurtado-Nedelec, Margarita, Liu, Dan, Marzaioli, Viviana, Thieblemont, Nathalie, Dang, Pham My-Chan, El-Benna, Jamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934299/
https://www.ncbi.nlm.nih.gov/pubmed/36626553
http://dx.doi.org/10.1073/pnas.2209184120