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ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes
Monocytes play a key role in innate immunity by eliminating pathogens, releasing high levels of cytokines, and differentiating into several cell types, including macrophages and dendritic cells. Similar to other phagocytes, monocytes produce superoxide anions through the NADPH oxidase complex, which...
Autores principales: | Tlili, Asma, Pintard, Coralie, Hurtado-Nedelec, Margarita, Liu, Dan, Marzaioli, Viviana, Thieblemont, Nathalie, Dang, Pham My-Chan, El-Benna, Jamel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934299/ https://www.ncbi.nlm.nih.gov/pubmed/36626553 http://dx.doi.org/10.1073/pnas.2209184120 |
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