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STING controls T cell memory fitness during infection through T cell-intrinsic and IDO-dependent mechanisms

Stimulator of interferon genes (STING) signaling has been extensively studied in inflammatory diseases and cancer, while its role in T cell responses to infection is unclear. Using Listeria monocytogenes strains engineered to induce different levels of c-di-AMP, we found that high STING signals impa...

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Detalles Bibliográficos
Autores principales: Quaney, Michael J., Pritzl, Curtis J., Luera, Dezzarae, Newth, Rebecca J., Knudson, Karin M., Saxena, Vikas, Guldenpfennig, Caitlyn, Gil, Diana, Rae, Chris S., Lauer, Peter, Daniels, Mark A., Teixeiro, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934307/
https://www.ncbi.nlm.nih.gov/pubmed/36634134
http://dx.doi.org/10.1073/pnas.2205049120