Cargando…
STING controls T cell memory fitness during infection through T cell-intrinsic and IDO-dependent mechanisms
Stimulator of interferon genes (STING) signaling has been extensively studied in inflammatory diseases and cancer, while its role in T cell responses to infection is unclear. Using Listeria monocytogenes strains engineered to induce different levels of c-di-AMP, we found that high STING signals impa...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934307/ https://www.ncbi.nlm.nih.gov/pubmed/36634134 http://dx.doi.org/10.1073/pnas.2205049120 |