IL-17A regulates autophagy and promotes osteoclast differentiation through the ERK/mTOR/Beclin1 pathway

Bone is a frequent target of tumor metastasis, with high incidence rate and poor prognosis. Osteoclasts play a key role in the process of tumor bone metastasis. Interleukin-17A (IL-17A) is an inflammatory cytokine, highly expressed in a variety of tumor cells, that can alter the autophagic activity...

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Detalles Bibliográficos
Autores principales: Tang, Hao, Zhu, Shida, Chen, Kai, Yuan, Shujie, Hu, Junzu, Wang, Hongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934321/
https://www.ncbi.nlm.nih.gov/pubmed/36795736
http://dx.doi.org/10.1371/journal.pone.0281845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934321/
https://www.ncbi.nlm.nih.gov/pubmed/36795736
http://dx.doi.org/10.1371/journal.pone.0281845

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