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Sodium thiosulfate through preserving mitochondrial dynamics ameliorates oxidative stress induced renal apoptosis and ferroptosis in 5/6 nephrectomized rats with chronic kidney diseases

Chronic kidney disease (CKD) progression may be evoked through dysregulated mitochondrial dynamics enhanced oxidative stress and inflammation contributing to high cardiovascular morbidity and mortality. Previous study has demonstrated sodium thiosulfate (STS, Na(2)S(2)O(3)) could effectively attenua...

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Detalles Bibliográficos
Autores principales: Cheng, Yu-Hsuan, Yao, Chien-An, Yang, Chih-Ching, Hsu, Shih-Ping, Chien, Chiang-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934356/
https://www.ncbi.nlm.nih.gov/pubmed/36795670
http://dx.doi.org/10.1371/journal.pone.0277652