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Differential modularity of the mammalian Engrailed 1 enhancer network directs sweat gland development
Enhancers are context-specific regulators of expression that drive biological complexity and variation through the redeployment of conserved genes. An example of this is the enhancer-mediated control of Engrailed 1 (EN1), a pleiotropic gene whose expression is required for the formation of mammalian...
Autores principales: | Aldea, Daniel, Kokalari, Blerina, Atsuta, Yuji, Dingwall, Heather L., Zheng, Ying, Nace, Arben, Cotsarelis, George, Kamberov, Yana G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934363/ https://www.ncbi.nlm.nih.gov/pubmed/36745673 http://dx.doi.org/10.1371/journal.pgen.1010614 |
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