Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection

Angiotensin-converting enzyme 2 (ACE2) is the cell-surface receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While its central role in Coronavirus Disease 2019 (COVID-19) pathogenesis is indisputable, there remains significant debate regarding the role of this transmembrane...

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Detalles Bibliográficos
Autores principales: Tang, Alan T., Buchholz, David W., Szigety, Katherine M., Imbiakha, Brian, Gao, Siqi, Frankfurter, Maxwell, Wang, Min, Yang, Jisheng, Hewins, Peter, Mericko-Ishizuka, Patricia, Leu, N Adrian, Sterling, Stephanie, Monreal, Isaac A., Sahler, Julie, August, Avery, Zhu, Xuming, Jurado, Kellie A., Xu, Mingang, Morrisey, Edward E., Millar, Sarah E., Aguilar, Hector C., Kahn, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934376/
https://www.ncbi.nlm.nih.gov/pubmed/36745682
http://dx.doi.org/10.1371/journal.pbio.3001989

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934376/
https://www.ncbi.nlm.nih.gov/pubmed/36745682
http://dx.doi.org/10.1371/journal.pbio.3001989

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