Ethyl pyruvate protects SHSY5Y cells against 6-hydroxydopamine-induced neurotoxicity by upregulating autophagy

Parkinson disease is a chronic progressive neurodegenerative disorder with a prevalence that increases with age. The glycolytic end-product pyruvate, has antioxidant and neuroprotective feature. Here, we investigated the effects of ethyl pyruvate (EP), a pyruvic acid derivative, on 6-hydroxydopamine...

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Detalles Bibliográficos
Autores principales: Luo, Yuening, Sakamoto, Kazuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934379/
https://www.ncbi.nlm.nih.gov/pubmed/36795720
http://dx.doi.org/10.1371/journal.pone.0281957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934379/
https://www.ncbi.nlm.nih.gov/pubmed/36795720
http://dx.doi.org/10.1371/journal.pone.0281957

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