Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release

Cyclic GMP-AMP synthase (cGAS) plays a key role in the innate immune responses to both DNA and RNA virus infection. Here, we found that enterovirus 71 (EV-A71), Seneca Valley virus (SVV), and foot-and-mouth disease virus (FMDV) infection triggered mitochondria damage and mitochondrial DNA (mtDNA) re...

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Detalles Bibliográficos
Autores principales: Liu, Huisheng, Zhu, Zixiang, Xue, Qiao, Yang, Fan, Li, Zongqiang, Xue, Zhaoning, Cao, Weijun, He, Jijun, Guo, Jianhong, Liu, Xiangtao, Shaw, Andrew E., King, Donald P., Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934381/
https://www.ncbi.nlm.nih.gov/pubmed/36745686
http://dx.doi.org/10.1371/journal.ppat.1011132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934381/
https://www.ncbi.nlm.nih.gov/pubmed/36745686
http://dx.doi.org/10.1371/journal.ppat.1011132

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