Cargando…
Innate sensing of picornavirus infection involves cGAS-STING-mediated antiviral responses triggered by mitochondrial DNA release
Cyclic GMP-AMP synthase (cGAS) plays a key role in the innate immune responses to both DNA and RNA virus infection. Here, we found that enterovirus 71 (EV-A71), Seneca Valley virus (SVV), and foot-and-mouth disease virus (FMDV) infection triggered mitochondria damage and mitochondrial DNA (mtDNA) re...
Autores principales: | Liu, Huisheng, Zhu, Zixiang, Xue, Qiao, Yang, Fan, Li, Zongqiang, Xue, Zhaoning, Cao, Weijun, He, Jijun, Guo, Jianhong, Liu, Xiangtao, Shaw, Andrew E., King, Donald P., Zheng, Haixue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934381/ https://www.ncbi.nlm.nih.gov/pubmed/36745686 http://dx.doi.org/10.1371/journal.ppat.1011132 |
Ejemplares similares
-
Picornavirus infection enhances aspartate by the SLC38A8 transporter to promote viral replication
por: Liu, Huisheng, et al.
Publicado: (2023) -
Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function
por: Wang, Congcong, et al.
Publicado: (2021) -
NOG1 downregulates type I interferon production by targeting phosphorylated interferon regulatory factor 3
por: Xue, Qiao, et al.
Publicado: (2023) -
Seneca Valley Virus 3C(pro) Cleaves PABPC1 to Promote Viral Replication
por: Xue, Qiao, et al.
Publicado: (2020) -
RINCK-mediated monoubiquitination of cGAS promotes antiviral innate immune responses
por: Liu, Zhao-Shan, et al.
Publicado: (2018)