Polymeric siRNA delivery targeting integrin-β1 could reduce interactions of leukemic cells with bone marrow microenvironment

Uncontrolled proliferation of the myeloid cells due to BCR-ABL fusion has been successfully treated with tyrosine kinase inhibitors (TKIs), which improved the survival rate of Chronic Myeloid Leukemia (CML) patients. However, due to interactions of CML cells with bone marrow microenvironment, sub-po...

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Detalles Bibliográficos
Autores principales: Meenakshi Sundaram, Daniel Nisakar, Kucharski, Cezary, Bahadur KC, Remant, Tarman, Ibrahim Oğuzhan, Uludağ, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934419/
https://www.ncbi.nlm.nih.gov/pubmed/36824309
http://dx.doi.org/10.1016/j.bbiosy.2021.100021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934419/
https://www.ncbi.nlm.nih.gov/pubmed/36824309
http://dx.doi.org/10.1016/j.bbiosy.2021.100021

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