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Polycaprolactone-collagen nanofibers loaded with dexamethasone and simvastatin as an osteoinductive and immunocompatible scaffold for bone regeneration applications

Physiological inflammation has been shown to promote bone regeneration; however, prolonged inflammation impedes the osteogenesis and bone repair process. To overcome the latter we aimed to develop a dual drug delivering nanofibrous scaffold to promote osteogenic differentiation of mesenchymal stroma...

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Detalles Bibliográficos
Autores principales: Rather, Hilal Ahmad, Varghese, Johnna Francis, Dhimmar, Bindiya, Yadav, Umesh C.S., Vasita, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934467/
https://www.ncbi.nlm.nih.gov/pubmed/36824372
http://dx.doi.org/10.1016/j.bbiosy.2022.100064