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Spacer length and serum protein adsorption affect active targeting of trastuzumab-modified nanoparticles

Receptor-mediated active targeting of nanocarriers is a widely investigated approach to specifically address cancerous cells and tissues in the human body. The idea is to use these formulations as drug carriers with enhanced specificity and therefore reduced systemic side effects. Until today a big...

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Detalles Bibliográficos
Autores principales: Barth, Christina, Spreen, Hendrik, Mulac, Dennis, Keuter, Lucas, Behrens, Matthias, Humpf, Hans-Ulrich, Langer, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934468/
https://www.ncbi.nlm.nih.gov/pubmed/36825111
http://dx.doi.org/10.1016/j.bbiosy.2021.100032