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Spacer length and serum protein adsorption affect active targeting of trastuzumab-modified nanoparticles
Receptor-mediated active targeting of nanocarriers is a widely investigated approach to specifically address cancerous cells and tissues in the human body. The idea is to use these formulations as drug carriers with enhanced specificity and therefore reduced systemic side effects. Until today a big...
Autores principales: | Barth, Christina, Spreen, Hendrik, Mulac, Dennis, Keuter, Lucas, Behrens, Matthias, Humpf, Hans-Ulrich, Langer, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934468/ https://www.ncbi.nlm.nih.gov/pubmed/36825111 http://dx.doi.org/10.1016/j.bbiosy.2021.100032 |
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