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Biodegradable nanoparticulate co-delivery of flavonoid and doxorubicin: Mechanistic exploration and evaluation of anticancer effect in vitro and in vivo

The proposed study involves delivering drug/bioactive using a single nanoplatform based on poly lactic-co-glycolic acid (PLGA) for better efficacy, synergistic effect, and reduced toxicity. PLGA was conjugated to doxorubicin (D1), and this conjugate was used for encapsulation of naringenin (D2) to d...

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Detalles Bibliográficos
Autores principales: Khan, Iliyas, Sarkar, Bibekananda, Joshi, Gaurav, Nakhate, Kartik T., Ajazuddin, Mantha, Anil K., Kumar, Raj, Kaul, Ankur, Chaturvedi, Shubhra, Mishra, Anil K., Gupta, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934469/
https://www.ncbi.nlm.nih.gov/pubmed/36824308
http://dx.doi.org/10.1016/j.bbiosy.2021.100022