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Biodegradable nanoparticulate co-delivery of flavonoid and doxorubicin: Mechanistic exploration and evaluation of anticancer effect in vitro and in vivo
The proposed study involves delivering drug/bioactive using a single nanoplatform based on poly lactic-co-glycolic acid (PLGA) for better efficacy, synergistic effect, and reduced toxicity. PLGA was conjugated to doxorubicin (D1), and this conjugate was used for encapsulation of naringenin (D2) to d...
Autores principales: | Khan, Iliyas, Sarkar, Bibekananda, Joshi, Gaurav, Nakhate, Kartik T., Ajazuddin, Mantha, Anil K., Kumar, Raj, Kaul, Ankur, Chaturvedi, Shubhra, Mishra, Anil K., Gupta, Umesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934469/ https://www.ncbi.nlm.nih.gov/pubmed/36824308 http://dx.doi.org/10.1016/j.bbiosy.2021.100022 |
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