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Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice

Nutrients are actively taken up by the brain via various transporters at the blood–brain barrier (BBB). A lack of specific nutrients in the aged brain, including decreased levels of docosahexaenoic acid (DHA), is associated with memory and cognitive dysfunction. To compensate for decreased brain DHA...

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Detalles Bibliográficos
Autores principales: Iwao, Takuro, Takata, Fuyuko, Matsumoto, Junichi, Aridome, Hisataka, Yasunaga, Miho, Yokoya, Miki, Kataoka, Yasufumi, Dohgu, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934487/
https://www.ncbi.nlm.nih.gov/pubmed/36795730
http://dx.doi.org/10.1371/journal.pone.0281946