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Speeding up interval estimation for R(2)-based mediation effect of high-dimensional mediators via cross-fitting
Mediation analysis is a useful tool in biomedical research to investigate how molecular phenotypes, such as gene expression, mediate the effect of an exposure on health outcomes. However, commonly used mean-based total mediation effect measures may suffer from cancellation of component-wise mediatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934518/ https://www.ncbi.nlm.nih.gov/pubmed/36798366 http://dx.doi.org/10.1101/2023.02.06.527391 |