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Diminishing neuronal acidification by channelrhodopsins with low proton conduction
Many channelrhodopsins are permeable to protons. We found that in neurons, activation of a highcurrent channelrhodopsin, CheRiff, led to significant acidification, with faster acidification in the dendrites than in the soma. Experiments with patterned optogenetic stimulation in monolayers of HEK cel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934520/ https://www.ncbi.nlm.nih.gov/pubmed/36798192 http://dx.doi.org/10.1101/2023.02.07.527404 |
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