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Deletion of transglutaminase 2 from astrocytes significantly improves their ability to promote neurite outgrowth on an inhibitory matrix

Astrocytes are the primary support cells of the central nervous system (CNS) that help maintain the energetic requirements and homeostatic environment of neurons. CNS injury causes astrocytes to take on reactive phenotypes with altered overall function that can range from supportive to harmful for r...

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Detalles Bibliográficos
Autores principales: Emerson, Jacen, Delgado, Thomas, Girardi, Peter, Johnson, Gail VW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934526/
https://www.ncbi.nlm.nih.gov/pubmed/36798305
http://dx.doi.org/10.1101/2023.02.06.527263