TFEB-vacuolar ATPase signaling regulates lysosomal function and microglial activation in tauopathy

Transcription factor EB (TFEB) mediates gene expression through binding to the Coordinated Lysosome Expression And Regulation (CLEAR) sequence. TFEB targets include subunits of the vacuolar ATPase (v-ATPase) essential for lysosome acidification. Single nucleus RNA-sequencing (snRNA-seq) of wild-type...

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Detalles Bibliográficos
Autores principales: Wang, Baiping, Martini-Stoica, Heidi, Qi, Chuangye, Lu, Tzu-Chiao, Wang, Shuo, Xiong, Wen, Qi, Yanyan, Xu, Yin, Sardiello, Marco, Li, Hongjie, Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934527/
https://www.ncbi.nlm.nih.gov/pubmed/36798205
http://dx.doi.org/10.1101/2023.02.06.527293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934527/
https://www.ncbi.nlm.nih.gov/pubmed/36798205
http://dx.doi.org/10.1101/2023.02.06.527293

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