Mechanisms of spinophilin-dependent pancreas dysregulation underlying diabesity

OBJECTIVE: Spinophilin is an F-actin binding and protein phosphatase 1 (PP1) targeting protein that acts as a scaffold of PP1 to its substrates. Spinophilin knockout (Spino(−/−)) mice have decreased fat mass, increased lean mass, and improved glucose tolerance, with no difference in feeding behavior...

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Detalles Bibliográficos
Autores principales: Stickel, Kaitlyn C., Mosley, Amber L., Doud, Emma H., Belecky-Adams, Teri L., Baucum, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934546/
https://www.ncbi.nlm.nih.gov/pubmed/36798361
http://dx.doi.org/10.1101/2023.02.07.527495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934546/
https://www.ncbi.nlm.nih.gov/pubmed/36798361
http://dx.doi.org/10.1101/2023.02.07.527495

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