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Mechanisms of spinophilin-dependent pancreas dysregulation underlying diabesity
OBJECTIVE: Spinophilin is an F-actin binding and protein phosphatase 1 (PP1) targeting protein that acts as a scaffold of PP1 to its substrates. Spinophilin knockout (Spino(−/−)) mice have decreased fat mass, increased lean mass, and improved glucose tolerance, with no difference in feeding behavior...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934546/ https://www.ncbi.nlm.nih.gov/pubmed/36798361 http://dx.doi.org/10.1101/2023.02.07.527495 |