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Restricting dietary protein or dietary isoleucine improves metabolic health in aged mice

A growing number of geroprotectors have demonstrated healthspan extension in young animals, but the effectiveness of these therapies when commenced in midlife or later has been under-studied. We and others have shown that much like calorie restriction (CR), restriction of specific nutrients, includi...

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Detalles Bibliográficos
Autores principales: Yeh, Chung-Yang, Chini, Lucas C.S., Gallagher, Meredith S., Davidson, Jessica W., Freichels, Isaac T., Calubag, Mariah F., Rodgers, Allison C., Green, Cara L., Babygirija, Reji, Sonsalla, Michelle M., Pak, Heidi H., Trautman, Michaela, Hacker, Timothy A., Simcox, Judith, Lamming, Dudley W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934591/
https://www.ncbi.nlm.nih.gov/pubmed/36798157
http://dx.doi.org/10.1101/2023.02.06.527311