Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection

Intracellular pathogens interact with host factors, exploiting those that enhance replication while countering those that suppress it. Genetic screens have begun to define the host:pathogen interface and establish a mechanistic basis for host-directed therapies. Yet, limitations of current approache...

Descripción completa

Detalles Bibliográficos
Autores principales: King, Cason R., Liu, Yiping, Amato, Katherine A., Schaack, Grace A., Hu, Tony, Smith, Judith A, Mehle, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934597/
https://www.ncbi.nlm.nih.gov/pubmed/36798235
http://dx.doi.org/10.1101/2023.02.07.527556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934597/
https://www.ncbi.nlm.nih.gov/pubmed/36798235
http://dx.doi.org/10.1101/2023.02.07.527556

Ejemplares similares