Individual recombinant repeats of MUC16 display variable binding to CA125 antibodies

BACKGROUND: Despite its importance in the clinical management of ovarian cancer, the CA125 biomarker—located on the mucin protein MUC16—is still not completely understood. Questions remain about MUC16’s function and structure, specifically the identity and location of the CA125 epitopes. OBJECTIVE:...

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Detalles Bibliográficos
Autores principales: Wang, Chien-Wei, Hanson, Eliza K., Minkoff, Lisa, Whelan, Rebecca J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934600/
https://www.ncbi.nlm.nih.gov/pubmed/36798296
http://dx.doi.org/10.1101/2023.02.08.527749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934600/
https://www.ncbi.nlm.nih.gov/pubmed/36798296
http://dx.doi.org/10.1101/2023.02.08.527749

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