Cargando…

Retrospective identification of intrinsic factors that mark pluripotency potential in rare somatic cells

Pluripotency can be induced in somatic cells by the expression of the four “Yamanaka” factors OCT4, KLF4, SOX2, and MYC. However, even in homogeneous conditions, usually only a rare subset of cells admit reprogramming, and the molecular characteristics of this subset remain unknown. Here, we apply r...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Naveen, Goyal, Yogesh, Dunagin, Margaret C., Cote, Christopher J., Mellis, Ian A., Emert, Benjamin, Jiang, Connie L., Dardani, Ian P., Reffsin, Sam, Raj, Arjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934612/
https://www.ncbi.nlm.nih.gov/pubmed/36798299
http://dx.doi.org/10.1101/2023.02.10.527870