Diffsig: Associating Risk Factors With Mutational Signatures

Somatic mutational signatures elucidate molecular vulnerabilities to therapy and therefore detecting signatures and classifying tumors with respect to signatures has clinical value. However, identifying the etiology of the mutational signatures remains a statistical challenge, with both small sample...

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Detalles Bibliográficos
Autores principales: Park, Ji-Eun, Smith, Markia A., Van Alsten, Sarah C., Walens, Andrea, Wu, Di, Hoadley, Katherine A., Troester, Melissa A., Love, Michael I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934616/
https://www.ncbi.nlm.nih.gov/pubmed/36798154
http://dx.doi.org/10.1101/2023.02.09.527740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934616/
https://www.ncbi.nlm.nih.gov/pubmed/36798154
http://dx.doi.org/10.1101/2023.02.09.527740

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