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Diffsig: Associating Risk Factors With Mutational Signatures
Somatic mutational signatures elucidate molecular vulnerabilities to therapy and therefore detecting signatures and classifying tumors with respect to signatures has clinical value. However, identifying the etiology of the mutational signatures remains a statistical challenge, with both small sample...
Autores principales: | Park, Ji-Eun, Smith, Markia A., Van Alsten, Sarah C., Walens, Andrea, Wu, Di, Hoadley, Katherine A., Troester, Melissa A., Love, Michael I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934616/ https://www.ncbi.nlm.nih.gov/pubmed/36798154 http://dx.doi.org/10.1101/2023.02.09.527740 |
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