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Modulation of GPR133 (ADGRD1) Signaling by its Intracellular Interaction Partner Extended Synaptotagmin 1 (ESYT1)

GPR133 (ADGRD1) is an adhesion G protein-coupled receptor that signals through Gαs and is required for growth of glioblastoma (GBM), an aggressive brain malignancy. The regulation of GPR133 signaling is incompletely understood. Here, we use proximity biotinylation proteomics to identify ESYT1, a Ca(...

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Detalles Bibliográficos
Autores principales: Stephan, Gabriele, Erdjument-Bromage, Hediye, Liu, Wenke, Frenster, Joshua D., Ravn-Boess, Niklas, Bready, Devin, Cai, Julia, Fenyo, David, Neubert, Thomas, Placantonakis, Dimitris G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934660/
https://www.ncbi.nlm.nih.gov/pubmed/36798364
http://dx.doi.org/10.1101/2023.02.09.527921