Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse

ARL13B is a small GTPase enriched in cilia. Deletion of Arl13b in mouse kidney results in renal cysts and an associated absence of primary cilia. Similarly, ablation of cilia leads to kidney cysts. To investigate whether ARL13B functions from within cilia to direct kidney development, we examined ki...

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Detalles Bibliográficos
Autores principales: Van Sciver, Robert E., Long, Alyssa B., Katz, Harrison G., Gigante, Eduardo D., Caspary, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934666/
https://www.ncbi.nlm.nih.gov/pubmed/36798281
http://dx.doi.org/10.1101/2023.02.08.527739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934666/
https://www.ncbi.nlm.nih.gov/pubmed/36798281
http://dx.doi.org/10.1101/2023.02.08.527739

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