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RNA polymerase sliding on DNA can couple the transcription of nearby bacterial operons

DNA transcription initiates after an RNA polymerase (RNAP) molecule binds to the promoter of a gene. In bacteria, the canonical picture is that RNAP comes from the cytoplasmic pool of freely diffusing RNAP molecules. Recent experiments suggest the possible existence of a separate pool of polymerases...

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Detalles Bibliográficos
Autores principales: Tenenbaum, Debora, Inlow, Koe, Friedman, Larry, Cai, Anthony, Gelles, Jeff, Kondev, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934669/
https://www.ncbi.nlm.nih.gov/pubmed/36798213
http://dx.doi.org/10.1101/2023.02.10.528045